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Examinando Producción Científica por Autor "Colque Ayma, Elvis Jack"
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Ítem Exploring a Sustainable Process for Polyphenol Extraction from Olive Leaves(MDPI, 2024-01-15) Huamán Castilla, Nils Leander; Díaz Huamaní, Karla Syndel; Palomino Villegas, Yolanda Cristina; Allcca Alca, Erik Edwin; León Calvo, Nilton Cesar; Colque Ayma, Elvis Jack; Zirena Vilca, Franz; Mariotti Celis, María SaloméOlive leaves are residues from pruning and harvesting and are considered an environmental management problems. Interestingly, these residues contain high polyphenol concentrations, which can be used to treat chronic diseases. However, these compounds are a technological challenge due to their thermolability and reactivity during extraction. Thus, this study assessed the use of pressurized liquid extraction (PLE) with green solvents like water-ethanol and water-glycerol mixtures (0–15%) at 50 °C and 70 °C to yield polyphenol-rich antioxidant extracts with reduced glucose and fructose content. The use of 30% ethanol at 70°C presented the highest polyphenol content (15.29 mg gallic acid equivalent/g dry weight) and antioxidant capacity, which was expressed as IC50 (half maximal inhibitory concentration): 5.49 mg/mL and oxygen radical absorbance capacity (ORAC): 1259 μmol Trolox equivalent/g dry weight, as well as lower sugar content (glucose: 3.75 mg/g dry weight, fructose: 5.68 mg/g dry weight) compared to water–glycerol mixtures. Interestingly, ethanol exhibits a higher degree of effectiveness in recovering flavanols, stilbenes and secoiridoids, while glycerol improves the extraction of phenolic acids and flavonols. Therefore, to enhance the efficiency of polyphenol recovery during the PLE process, it is necessary to consider its solvent composition and chemical structure. Keywords: olive leaves; polyphenols; antioxidant capacity; pressurized liquid extraction; green solventÍtem Presence and leaching of PAHs in soils of high Andean grasslands affected by intentional burning.(Elsevier, 2024-05) Vega Quispe, Anyela Pierina; Merma Chacca, Donald Efrain; Maldonado, Ingrid; Colque Ayma, Elvis Jack; Guimarães Guilherme, Luiz Roberto; Jiménez Jiménez, Paúl Andrés; Rivera Campano, Milko Raúl; Ramos Tejeda, José Luis; Zirena Vilca, FranzInteractions between host and pathogenic microorganisms are common in nature and have a significant impact on host health, often leading to several types of infections. These interactions have evolved as a result of the ongoing battle between the host’s defense mechanisms and the pathogens’ invasion strategies. In this chapter, we will explore the evolution of host-pathogen interactions, explore their molecular mechanisms, examine the different stages of interaction, and discuss the development of pharmacological treatments. Understanding these interactions is crucial for improving public health, as it enables us to develop effective strategies to prevent and control infectious diseases. By gaining insights into the intricate dynamics between pathogens and their hosts, we can work towards reducing the burden of such diseases on society.